Spinal Infusion

spinal infusion
I need help on a case study for my pharmacology class?

There is a 49 year old man who experienced a spinal cord injury 20 years ago. This injury resulted in paraplegia. He has been hospitalized frequently for sepsis secondary to infected decubitus ulcers on his buttocks. He presently is being treated with vancomycin for MRSA found in his decubitus wound culture. His prescriptions include:

Placement of a peripherally inserted central catheter (PICC)
Vancomycin 1 g intravenously every 12 hours
Routine central venous access device care
and Vancomycin peak and trough after third dose

1. Discuss major adverse effects of vancomycin
2. Discuss “red man syndrome” and its relationship to vancomycin
3. Discuss the rationale for using vancomycin to treat his wound infection.
4. Discuss the reason for proscribing a peak antd trough for vancomycin.
5. Why is he prescribed the placement of a PICC for vancomycin infusion?

1. Discuss major adverse effects of vancomycin – Allergic reaction
2. Discuss “red man syndrome” and its relationship to vancomycin – Don’t know
3. Discuss the rationale for using vancomycin to treat his wound infection. – Vanco is one of the few antibiotics to treat MRSA…it is resistant to many of the routine antibiotics used to treat infection
4. Discuss the reason for proscribing a peak antd trough for vancomycin. – Vanco is one of those drugs that needs to be adjusted according to “levels” of it found in the blood. You do a trough (before administration) and peak (30 min – 1 hour after administration) to determine whether the dosage needs to be adjusted
5. Why is he prescribed the placement of a PICC for vancomycin infusion? PICCs are placed many times for long term antibiotic therapy. They can stay in place for 6-8 weeks and reduce the chance of infecting peripheral IV sites.

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